The ZEO Brand has been manufacturing deuterated compounds since the 1970s, used in fields such as active pharmaceutical ingredients (APIs) and organic light-emitting diodes (OLEDs).
These compounds also function as critical solvents in NMR spectroscopy.
In line with our goal of always introducing innovative products to the market, ZEOchem continuously expands its product range. Our Research and Development (R&D) team is ready to develop products that precisely meet your requested specifications.
Applications
Scientific and Industrial Applications of Deuterated Compounds
Zeochem plays a pioneering role in the production of deuterated compounds required by the scientific community and high-tech industries. Offering a wide range of solutions from active pharmaceutical ingredients (APIs) to organic light-emitting diodes (OLEDs), our company continuously expands its product range with an R&D-focused approach and manufactures according to custom specifications based on customer demands.
The primary application areas and the added value provided by Zeochem products are grouped under three main headings:
NMR
Nuclear Magnetic Resonance spectroscopy, most commonly known as NMR spectroscopy, is a technique based on the principle of observing magnetic fields around atomic nuclei.
Pharma
ZEOchem offers a wide range of high-quality Deuterated Compounds specifically for the industrial synthesis of Deuterium-Labeled Active Pharmaceutical Ingredients (APIs).
Electronics
ZEOchem offers Deuterated Compounds to the market, specifically developed for solutions in the electronics sector.
Questions About Our Products
Frequently Asked Questions
Zeochem manufactures deuterated compounds used in fields such as active pharmaceutical ingredients (APIs) and organic light-emitting diodes (OLEDs). Additionally, these compounds serve as critical solvents for NMR spectroscopy in analytical chemistry laboratories.
What additives or stabilizers might Chloroform-d contain?
Offered for high-resolution NMR performance, Chloroform-d can be supplied with additives such as Silver foils (Ag) and/or Tetramethylsilane (TMS) depending on your needs. Additionally, this product is available in the highest chemical and isotopic purity (99.8% and 99.95% atom %D).
Do you offer a less toxic and highly environmentally safe alternative compared to standard NMR solvents?
Yes, 2-Propanol-d8 (Isopropanol-d8) exhibits lower toxicity and higher environmental safety compared to frequently used solvents such as Methanol-d4 or Chloroform-d. This solvent is also compatible with a wide range of organic and organometallic compounds.
Which chemical shift references are used for H NMR analyses in aqueous solutions?
For analyses conducted in aqueous solutions, DSS (3-(Trimethylsilyl)-1-propanesulfonic acid sodium salt) or TSP-d4 (3-(Trimethylsilyl)propionic-2,2,3,3-d4 acid sodium salt) are recommended. Both compounds are soluble in water or deuterium oxide and function as chemical shift references.
Are any precautions taken to prevent the polymerization of Styrene-d8 during storage?
Yes, commercially available Styrene-d8 contains 4-tert-Butylcatechol to maintain product stability and prevent unwanted polymerization.
What technical differences do Deuterated Active Pharmaceutical Ingredients (APIs) offer compared to traditional drugs?
Deuterated APIs provide pharmacological advantages through the "kinetic isotope effect." This effect improves the metabolic profiles of drugs, increases oral bioavailability, and can reduce dosage requirements compared to traditional APIs.
